Pharma Plant | Research&Development

Innovative Science, Strong Future

“With our vision shaped by science, we add value to human health.”

As Pharma Plant Pharmaceuticals, we invest in scientific researches in order to shape health for the future. Our R&D center operates to create new generation treatment options, offer more efficient formulations and produce better overall quality products.

Our R&D Processes

Our medicine manufacturing processes are bound tightly to scientific accuracy, regulation eligibility and quality standards.
You can find every stage in detail, down below:

Pre-Formulation

Physicochemical characterization of the original product and active pharmaceutical ingredient (API)
Compatibility studies of the API (Active Pharmaceutical Ingredient) with excipients
Determination of the formulation strategy through risk assessment

Bioequivalence Studies

Conducting studies to demonstrate the bioavailability of the formulation
Repeating compatibility and risk assessments with excipients
Preparing the necessary documentation for clinical trials

Pilot Scale Studies

Scale-up from laboratory scale to pilot scale
Optimization of the pilot-scale production process
Conducting trial productions
Pilot batch production and conducting stability tests

Laboratory Scale Studies

Determination of the appropriate production process
Development of the production process at lab scale
Finalization of the formulation and approval of the final formula
Initiation of stability studies

Licensing Process

Preparation of CTD (Common Technical Document) files to be submitted to authorities
Application process to the health authority and follow-up of authority evaluations
Submission of additional information and corrections to ensure regulatory compliance

Supply Chain Management

Selection of suitable suppliers for API and excipients
Determination of economical and reliable transportation methods
Obtaining import permits and managing the import process
Managing customs procedures and tracking documentation
Ensuring timely delivery for production and distribution

Technologies Used

pH Meters and Conductivity Meters
Used to determine the basic physicochemical properties of formulations.

Titration Systems (Potentiometric or Karl Fischer)
Used in moisture analysis and other quantitative analyses (especially for water content determination).

FTIR (Fourier Transform Infrared Spectroscopy)
Used for detailed analysis of molecular structures.

UV-VIS Spectrophotometry
Widely used in the analysis of colored compounds.

High-Performance Liquid Chromatography (HPLC)
Provides precise and reliable results in the analysis of active ingredients.

Gas Chromatography (GC)
Used for the analysis of volatile compounds, particularly suitable for detecting residual organic solvents.

Dissolution Devices
Measure tablet dissolution rates, providing insights into bioavailability.

Transdermal Diffusion Cells (Franz Diffusion Cells)
Used to assess the permeation of the active ingredient through the skin. They are critical for determining the absorption profiles of transdermal and topical products.

Microbiological Safety Cabinets and Incubators
Essential for sterility testing and microbiological quality control.

Stability Chambers (Compliant with ICH Conditions)
Used to test the durability of products under climate-controlled conditions.